Kugeza ubu, hari ubwoko 81 bwimiti igabanya ubukana ikoreshwa mubuvuzi.1. Imiti irwanya ibibyimba ishyirwa mubikorwa ukurikije inkomoko hamwe nuburyo bwo gukora.Mubisanzwe bigabanijwemo imiti ya alkylating, antimetabolite, antibiotique, ibimera, imisemburo nindi miti.Ibindi biyobyabwenge birimo platine, asparaginase, imiti igamije kuvura, nibindi, usibye reagent biologique hamwe nubuvuzi bwa gene.Iri tsinda ntirishobora kuvuga muri make iterambere ryimiti igabanya ubukana.Icya kabiri, ikindi cyiciro gishingiye ku ntego ya molekuline yibiyobyabwenge, bigabanijwemo ibyiciro byinshi.Icyiciro cya mbere ni ibiyobyabwenge bikora kumiterere ya ADN, nka alkylating cyangwa platine.Icyiciro cya kabiri ni ibiyobyabwenge bigira ingaruka kuri acide nucleic aside, nka antimetabolite.Icyiciro cya gatatu ni ibiyobyabwenge bikora ku cyitegererezo cya ADN, bigira ingaruka ku kwandukura no kubuza ADN, kandi bikabuza synthesis ya RNA bishingiye kuri polymerase ya RNA.Icyiciro cya kane ni ibiyobyabwenge bigira ingaruka kuri synthesis, nka paclitaxel, vinblastine nibindi.Icyiciro cyanyuma nubundi bwoko bwibiyobyabwenge, nka hormone, aside aspartic, imiti igamije kuvura, nibindi, ariko imiti igabanya ubukana iratera imbere byihuse, kandi ibyiciro byavuzwe haruguru ntibishobora kuvuga muri make ibiyobyabwenge bihari nibiyobyabwenge biri hafi kwinjira mu ivuriro..“

Kugeza ubu, hari imiti myinshi irwanya ibibyimba mubikorwa byubuvuzi.Kurugero,oxaliplatin, fluorouracil, na irinotecan irashobora gukoreshwa mubyimba gastrointestinal.Abarwayi ba kanseri yo mu gifu barashobora kuvurwa nibiyobyabwenge nkacisplatinnapaclitaxel.Muri rusange, kanseri zitandukanye zihitamo imiti itandukanye.Byongeye kandi, abarwayi ba kanseri barashobora kandi kuvurwa hakoreshejwe imiti igabanya ubukana nka erlotinib, osimertinib, cetuximab n'ibindi biyobyabwenge

Imiti isanzwe irwanya ibibyimba itera CIPN harimoYamazaki, Platinum, Vinblastine,Methotrexate, Fluorouracil, Ifosfamide,Cytarabine, Fludarabine, Thalidomide,Bortimiazolen'ibindi.

Paclitaxel ikoresha imikurire yimitsi kugirango igabanye cyangwa ihindure neurotoxicity;cisplatine ikoresha glutathione na amifostine yagabanutse kugirango birinde neuropathie iterwa nayo;oxaliplatine ntabwo ihura nubukonje mugihe cyo kuyikoresha kugirango ikumire ubukonje butagira ingaruka ku mitsi ya periferique Stimulation, gukoresha imvange ya calcium-magnesium irashobora kugabanya ubwinshi nuburemere bwibimenyetso bikaze bya neurotoxicity, kandi bigatinda kubaho kwa neuropathie cumulative;ifosfamide irashobora guhitamo methylene ubururu kugirango wirinde neurotoxicity;koresha thiamine kuri fluorouracil irashobora gukumira imitsi Ingaruka zuburozi.